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Successful Transvaginal Aspiration of Cervical Pregnancy after Failed Methotrexate Treatment: A Case Report

Background: Cervical pregnancies are infrequent and fatal. Systemic methotrexate (MTX) treatment is conventionally administered to preserve fertility and prevent hemorrhage. However, some patients do not respond to therapy.

Methods: Transvaginal aspiration because MTX treatment failed.

Results: Two cases were successfully treated by transvaginal aspiration. Serial ultrasound exams and blood beta-hCG confirmed resolution of cervical pregnancy.

Conclusion: Our results suggest that transvaginal aspiration should be considered an alternative upon failure of systemic MTX treatment or in the presence of contraindications for MTX injection.


Fang Y1, Yu-Hung L1-4,
Jiann-Loung H1,
Lee-Wen H1-3,
Ting-Chi Huang1-3 and
Chun-Cheng Chu1

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