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Case Report of Cardiac Metastasis from Cervical Squamous Carcinoma and its Literature Review

We reported a case of a symptomatic metastasis of squamous cell carcinoma of the uterine cervix (SCCUC) to the right ventricle, then to the right atrium and superior vena cava five years later than the first SCCUC diagnosis. Because of the persistent thrombocytopenia, the treatment was discontinued after only one cycle of reduced paclitaxel liposome five years ago. The patient died six weeks after the diagnosis of cardiac metastasis. We reviewed the literatures in last two decades for the epidemiology, clinical presentaion, diagnosis, treatment and prognosis of SCCUC with cardiac metastasis (SCCUCCM). Dyspnea and chest pain are the common clinical presentations. Echocardiography, cardiac computed tomography (CT) and cardiac magnetic resonance imaging (CMR) are recommended in diagnosis. The prognosis for cardiac metastasis is extremely poor, with a median survival time of 5 months. Thrombocytopenia is a negative factor in the survival time of SCCUC-CM. Aggressive therapy including surgical intervention, chemotherapy, and whole heart radiation therapy may prolong survival time.


Mingwei Yang, Lin Yang, Fan Wang, Xuegong Shi, Hao Wang, Qibing Wu, Yin Lv and Xiangxun Chen

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