A 19 cm Angiomyxoma of the Vulva in a 45-Year-Old Woman: A Case Report

Angiomyxoma is a rare, benign, locally infiltrative mesenchymal tumor that occurs in women at reproductive age. We present a 45-year-old female's case with a four years history of vaginal growth which has been progressively increasing in size. The patient was misdiagnosed of Bartholin's duct cysts and was asymptomatic. Aggressive angiomyxoma is a frequently misdiagnosed tumor that tends to recur locally. The prefix “aggressive” was added to emphasize this tumor characteristic. The diagnosis was based on histopathological and immuno-histochemical results. Treatment involves surgery that should aim wide local excision. However, over the years alternative treatment was proposed, in particular, hormonal therapy based on the female hormone receptors of this mesenchymal tumor. Application of imaging method, like ultrasounds, could be useful both for differential diagnosis and to evaluate the tumor before surgery. The frequent local recurrence of this disease requires a long-term follow-up.

Author(s):

Ietto C1*, Giannini A2,
Perutelli A2, Pistolesi S2,
Pancetti F2, Mannella P2 and
Simoncini T2

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